This one took me on a rollercoaster. "Oh, neat, like 'Nightcrawler!" Then, I will admit, I almost turned it off when the "escape mental patients" showed up. I am not a fan of crazy=evil as a trope. But I also trust Psuedopod, so I kept with it, and hooray, monsters. And so all is well with the world.
I just wish that some of Wesley's musings at the start of the story had tied more strongly back into this whole "mother of monsters, ultimate darkness" that shows up at the end. She was cool and deserved more foreshadowing.
The motif of the asylum and the title reminded me of Outlast, a video game which greatly disappointed me in a sort of reverse enthusiasm curve to the one described above. I went into (watching a playthrough of) it expecting it to be crazy=evil, but then the middle gives it a twist where the asylum has a story about a monster that, like Slenderman, thrives on being known, and to me this was a perfect explanation for a survival-horror game protagonist; you have to learn about the monster, but then you have to survive, if just barely, to tell the world and thus spread the curse. And as the protag is a journalist, it all fit perfectly. (Then they wimped out and went back to "No, it was actually just crazy murderers all along, but they were being experimented on by evil doctors so gosh what is morality anyway?")