I think it's pretty clear we're supposed to dislike Angie before she commits the murder, though. The doctor's desire to hand over the bag for the general benefit of all humankind is contrasted to Angie's desire to make more money specifically through the use of a new cosmetic surgery technique. The murder and subsequent accidental suicide flow from that, and I think at least in part, we're supposed to see this as her comeuppance for her ambition and the "obvious" shallowness of cosmetic surgery itself. Let's not forget all the bits about Angie and finishing school, which strengthen her association with female vanity.
Sure, I disliked her before the murder. But I didn't particularly like the doctor either. The doctor's desire to hand over the bag for the benefit of all mankind was portrayed explicitly as being a selfish act, despite the obvious good for humanity:
1. He wanted to be acknowledged for it.
2. He wanted to do this good thing to counterbalance the bad things he'd done in his life, not
because it was a good thing.
3. He wanted to do this good thing in large part because he was old and making tons of money at this stage of his life wasn't all that appealing to him.
4. He wanted to do this because of the benefits to himself primarily, and secondarily because of the benefits to humanity ,
but did not think at all about what he was asking Angie to give up for nothing.
The crime that HE died for was lack of empathy because he didn't think about her position, how she would lose everything by allowing him to do what he proposed. If he had any empathy he could've at least conceived an outcome that would also benefit Angie, such as giving her credit for the discovery to make her a celebrity. Whether he liked her or not, they'd been working together for quite some time. Even if he only cared what she thought for reasons of self-preservation, that would've been something.
She, on the other hand, was just trying to live the 1950s red-blooded American dream of financial prosperity through capitalism--she was the very model of an American hero of the time. Where that went awry was where the doctor tried to force his will upon her, and she responded to his crime with a crime of her own, and they both died as part of that exchange.